QUAREP-LiMi WG3 was pleased to host a webinar presented by Daniel Schröder on the topic of the "Universal Laser Engine" with an improved homogeneous illumination profile.
The webinar introduced a versatile laser excitation platform designed for advanced fluorescence microscopy and highlighted its applications across multiple imaging modalities.
Abstract
The Universal Laser Engine is a user-friendly laserbox designed to provide a versatile excitation for advanced fluorescence microscopy. In a single box, it holds up to 6 laser wavelengths operating in modes ranging from picosecond-pulsed to continuous-wave, enabling its use across a wide range of imaging modalities. The Universal Laser Engine has been successfully tested in widefield microscopy, super-resolution localization microscopy, total internal reflection fluorescence (TIRF), and fluorescence lifetime imaging microscopy (FLIM).
In addition, the Universal Laser Engine incorporates a novel speckle-suppression technology that generates a highly homogeneous flat-top hat profile that is applicable for high-speed imaging at exposure times down to microseconds. The system provides various trigger inputs and two fiber outputs for seamless integration into both existing and new microscopes. By combining flexibility, compact design, and state-of-the-art illumination uniformity, the Universal Laser Engine offers a powerful and adaptable solution for simplifying and modernizing fluorescence microscopy instrumentation.
Watch the webinar recording
